Responding to the increasing calls from the public, NGOs and other stakeholders in the region and amidst the changing global environment, the CARICOM Conference of Heads of Government at its Twenty-Fifth Inter-Sessional Meeting convened in St. Vincent and the Grenadines, 10 -11 March 2014, mandated the establishment of a Commission to interrogate the issue of possible reform to the legal regimes regulating cannabis/ marijuana in CARICOM countries.